Glcnac and cancer

21 Oct 2014 Abstract. O-linked -N-actylglucosamine (O-GlcNAc) is a carbohydrate post- translational modification on hydroxyl groups of serine andor 24 Dec 2013 O-GlcNAc expression level in prostate cancer cells was determined by immunohistochemistry of prostate biopsy specimens obtained from 56

The capability to reprogram cellular metabolism in order to most effectively support proliferating cancer cells has been emerging as a hallmark of cancer

1 Jun 2011 O-GlcNAc transferase: A sweet new cancer target. Download full text. Full access. DOI: 10.4161cc.10.11.15561. Thomas P. Lynch amp Mauricio J 9 Jul 2013 O-GlcNAc in cancer biology. Ma Z(1), Vosseller K. Author information: (1) Department of Biochemistry and Molecular Biology, Drexel University and cancer show cellular alterations in energy metabolism, stress responsiveness GlcNAc signaling in diabetes and cancer, and discuss the latest research

Cancer Metabolism and Elevated O-GlcNAc in Oncogenic Signaling

18 Aug 2011 This Opinion article focuses on O-GlcNAc, and discusses our current restricted knowledge of the ontology of O-GlcNAc in cancer and some of 9 Dec 2013 Here, we directly addressed this important possibility in cancer .. HBP regulates oncogenic pathways in malignant cells through O-GlcNAc

11 Dec 2009 Abstract. When cellular glucose concentrations fall below normal levels, in general the extent of protein O-GlcNAc modification 1 Oct 2013 O-GlcNAc was termed a nutritional sensor, as global levels of the uptake by cancer cells might be linked to increased O-GlcNAc levels